TY - GEN AU - Jiménez-Moreno, Carmen María AU - Martin-Montalvo, Alejandro AU - Álvarez Mercado, Ana Isabel AU - Fuente-Martin, Esther AU - Cobo-Vuilleumier, Nadia AU - Lorenzo, Petra Isabel AU - Bru-Tari, Eva AU - Herrera-Gómez, Irene de Gracia AU - López-Noriega, Livia AU - Pérez Florido, Javier AU - Santoyo-López, Javier AU - Spyrantis, Andreas AU - Meda, Paolo AU - Boehm, Bernhard O. AU - Quesada, Ivan AU - Gauthier, Benoit R. AU - Mellado-Gil, José Manuel PY - 2016 SN - 0012-186X SN - 1432-0428 UR - https://hdl.handle.net/10481/109591 AB - Aims/hypothesis: A strategy to enhance pancreatic islet functional beta cell mass (BCM) while restraining inflammation, through the manipulation of molecular and cellular targets, would provide a means to counteract the deteriorating glycaemic control... LA - eng PB - Springer KW - Beta cell degeneration KW - ER homeostasis KW - Type 1 diabetes (T1D) TI - PAX4 preserves endoplasmic reticulum integrity preventing beta cell degeneration in a mouse model of type 1 diabetes mellitus. DO - doi: 10.1007/s00125-016-3864-0 ER -