TY - GEN AU - Torres De Pinedo, Jesús Manuel AU - Habib, Abdella M AU - Shengman, Li AU - Zhan, Chenjing AU - Meijun, Ji AU - Osorio, Nancy AU - Penalba, Virginie AU - Gossage, Samuel J AU - Rezai, Mehdi A AU - Geard, Amy F AU - Rahim, Ahad A AU - Mahmoud, Ahmed MM AU - Santana-Varela, Sonia AU - Zhou, Jun AU - Zhao, Jing AU - Wood, John N. AU - Okorokov, Andrei L AU - Zhou, Xuelong AU - Cox, James J AU - Coste, Bertrand PY - 2025 UR - https://hdl.handle.net/10481/108919 AB - PIEZO channels are mechanical force sensors involved in various biological processes, including somatosensation. To date, only a few PIEZO-binding partners have been identified, including MyoD-family inhibitor proteins (MDFI and MDFIC). Here, we show... LA - eng PB - PNAS KW - Piezo channel KW - Mechanical allodynia KW - Neuropathic pain TI - MDFIC2 is a PIEZO channel modulator that can alleviate mechanical allodynia associated with neuropathic pain DO - 10.1073/pnas.2512426122 ER -