TY - GEN AU - Gutiérrez Rus, Luis Ignacio AU - Vos, Eva AU - Pantoja-Uceda, David AU - Hoffka, Gyula AU - Gutierrez-Cardenas, Jose AU - Ortega Muñoz, Mariano AU - Risso, Valeria Alejandra AU - Jimenez, Maria Angeles AU - Kamerlin, Shina C L AU - Sánchez Ruiz, José Manuel PY - 2025 UR - https://hdl.handle.net/10481/107797 AB - Enzymes are the quintessential green catalysts, but realizing their full potential for biotechnology typically requires improvement of their biomolecular properties. Catalysis enhancement, however, is often accompanied by impaired stability. Here, we... LA - eng PB - ACS TI - Enzyme Enhancement Through Computational Stability Design Targeting NMR-Determined Catalytic Hotspots DO - https://doi.org/10.1021/jacs.4c09428 ER -