TY  - GEN 
AU  - Carretero Coca, Rafael
PY  - 2023
UR  - https://hdl.handle.net/10481/107616
AB  - Background: The metabolism of tryptophan to kynurenines (KYN) by indoleamine-2,3-dioxygenase or tryptophan-2,3-dioxygenase is a key pathway of constitutive and adaptive tumor immune resistance. The immunosuppressive effects of KYN in the tumor...
LA  - eng
PB  - BioMed Central
KW  - Cancer
KW  - Drug discovery
KW  - Immunotherapy
KW  - AHR
TI  - Targeting the aryl hydrocarbon receptor (AhR) with BAY 2416964: a selective small molecule inhibitor for cancer immunotherapy
DO  - 10.1136/jitc-2023-007495
ER  -