TY  - GEN 
AU  - Álvarez Pérez, Juan Carlos
AU  - Sanjuan Hidalgo, Juan
AU  - Arenas, Alberto M.
AU  - Hernández-Navas, Iván
AU  - Benítez Cantós, María Soledad
AU  - Andrades Delgado, Álvaro
AU  - Calabuig-Fariñas, Silvia
AU  - Jantus-Lewintre, Eloisa
AU  - Paz-Ares, Luis
AU  - Ferrer, Irene
AU  - Medina Vico, Pedro Pablo
PY  - 2025
UR  - https://hdl.handle.net/10481/107558
AB  - Missense mutations in the 12th codon of KRAS are key drivers of lung cancer, with glycine-to-cysteine (G12C) and glycine-to-aspartic acid (G12D) substitutions being among the most prevalent. These mutations are strongly associated with poor survival...
LA  - eng
PB  - Springer Nature
TI  - High-fidelity Cas9-mediated targeting of KRAS driver mutations restrains lung cancer in preclinical models
DO  - 10.1038/s41467-025-62350-4
ER  -