TY  - GEN 
AU  - Córdoba-Gómez, Laura B.
AU  - Lorente-Macías, Álvaro
AU  - Loza, Maria Isabel
AU  - Brea, José
AU  - Martínez, Antón Leandro
AU  - Mok, Jonathon
AU  - King, Ben
AU  - Franco-Montalban, Francisco
AU  - González García, Antonio
AU  - Guardia-Monteagudo, Juan Jose
AU  - Matos, Maria
AU  - Unciti-Broceta, Asier
AU  - Diaz-Mochon, Juan Jose
AU  - Pineda de las Infantas, María J.
PY  - 2025
UR  - https://hdl.handle.net/10481/107503
AB  - The therapeutic potential of adenosine receptor (AR) ligands is becoming increasingly important as our understanding of the physio-pathological functions of ARs advances. This study presents the synthesis and biological screening of six novel...
LA  - eng
KW  - Adenine scaffold
KW  - docking simulation
KW  - cancer cell lines
KW  - antiproliferation
KW  - orthosteric binding site
TI  - Exploring Trisubstituted Adenine Derivatives as Adenosine A1 Receptor Ligands with Antagonist Activity: Synthesis, Biological Evaluation and Molecular Modelling
DO  - 10.1016/j.bioorg.2025.108395
ER  -