TY - GEN AU - Mora, Fernando AU - Ramos-Quiroga, Jose Antoni AU - Baca-García, Enrique AU - Crespo, José Manuel AU - Gutiérrez-Rojas, Luis AU - Madrazo, Aránzazu AU - Pérez-Costillas, Lucía AU - Saiz, Pilar A. AU - Tordera, Vicente AU - Vieta, Eduard PY - 2025 UR - https://hdl.handle.net/10481/106313 AB - Introduction: Depression is a highly prevalent disease that severely impacts the life of patients. Inadequate response to at least two antidepressants despite adequacy of treatment and adherence is known as treatment-resistant depression (TRD), which... LA - eng PB - Frontiers Research Foundation KW - intranasal esketamine KW - Definition KW - Therapeutic inertia TI - Treatment-resistant depression and intranasal esketamine: Spanish consensus on theoretical aspects DO - 10.3389/fpsyt.2025.1623659 ER -