TY - GEN AU - Parada, Esther AU - Casas, Ana I AU - Palomino-Antolín, Alejandra AU - Gomez-Rangel, Vanessa AU - Rubio-Navarro, Alfonso AU - Farré-Alins, Victor AU - Narros-Fernandez, Paloma AU - Guerrero-Hue, Melania AU - Moreno, Juan Antonio AU - Rosa, Juliana M AU - Roda, José M AU - Hernandez-Garcia, Borja J AU - Egea, Javier PY - 2019 UR - https://hdl.handle.net/10481/101217 AB - Background and purpose: Ischaemic stroke is a leading cause of death, disability, and a high unmet medical need. Post-reperfusion inflammation and an up-regulation of toll-like receptor 4 (TLR4), an upstream sensor of innate immunity, are associated... LA - eng PB - The British Pharmacological Society. TI - Early toll-like receptor 4 blockade reduces ROS and inflammation triggered by microglial pro-inflammatory phenotype in rodent and human brain ischaemia models DO - 10.1111/bph.14703 ER -