TY  - GEN 
AU  - Ranea-Robles, Pablo
AU  - Violante, Sara
AU  - Argmann, Carmen
AU  - Dodatko, Tetyana
AU  - Bhattacharya, Dipankar
AU  - Chen, Hongjie
AU  - Yu, Chunli
AU  - Friedman, Scott L.
AU  - Puchowicz, Michelle
AU  - Houten, Sander M.
PY  - 2021
UR  - https://hdl.handle.net/10481/100881
AB  - Peroxisomes play an essential role in the β-oxidation of dicarboxylic acids (DCAs), which are metabolites formed upon ω-oxidation of fatty acids. Genetic evidence linking transporters and enzymes to specific DCA β-oxidation steps is generally lacking....
LA  - eng
KW  - peroxisomes
KW  - dicarboxylic acids
KW  - Crispr
KW  - cholesterol
TI  - Murine deficiency of peroxisomal L-bifunctional protein (EHHADH) causes medium-chain 3-hydroxydicarboxylic aciduria and perturbs hepatic cholesterol homeostasis
DO  - 10.1007/s00018-021-03869-9
ER  -