TY  - GEN 
AU  - Tejada, Miguel Angel
AU  - Montilla-García, Angeles
AU  - Cronin, Shane J
AU  - Cikes, Domagoj
AU  - Sanchez-Fernandez, Cristina
AU  - Gonzalez-Cano, Rafael
AU  - Ruiz-Cantero, Maria del Carmen
AU  - Penninger, Josef M
AU  - Vela, Jose Miguel
AU  - Baeyens, Jose Manuel
AU  - Cobos, Enrique Jose
PY  - 2017
UR  - https://hdl.handle.net/10481/100231
AB  - Sigma-1 antagonism potentiates the antinociceptive effects of opioid drugs, so sigma-1 receptors constitute a biological brake to opioid drug-induced analgesia. The pathophysiological role of this process is unknown. We aimed to investigate whether...
LA  - eng
PB  - Proceedings of the National Academy of Sciences of the United States of America (PNAS)
KW  - endogenous opioid peptides
KW  - immune cells
KW  - inflammatory pain
KW  - sigma-1 receptors
TI  - Sigma-1 receptors control immune-driven peripheral opioid analgesia during inflammation in mice
DO  - 10.1073/pnas.1620068114
ER  -