Auditory brainstem and middle latency responses recorded at fast rates with randomized stimulation Valderrama Valenzuela, Joaquín Tomás Torre Vega, Ángel De La Ruiz Álvarez, Isaac Manuel Segura Luna, José Carlos Thornton, Arthur Roger David Sainz Quevedo, Manuel Vargas, Jose L This paper has been supported by research project TEC2009-14245, R&D National Plan (2008–2011), Ministry of Finance and Competition (Government of Spain); by research project GENIL-PYR 2014, Campus of International Excellence, Ministry of Finance and Competition (Government of Spain); and by Grant No. AP2009-3150 (FPU), Ministry of Education, Culture, and Sport (Government of Spain). Randomized stimulation and averaging (RSA) allows auditory evoked potentials (AEPs) to be recorded at high stimulation rates. This method does not perform deconvolution and must therefore deal with interference derived from overlapping transient evoked responses. This paper analyzes the effects of this interference on auditory brainstem responses (ABRs) and middle latency responses (MLRs) recorded at rates of up to 300 and 125 Hz, respectively, with randomized stimulation sequences of a jitter both greater and shorter than the dominant period of the ABR/MLR components. Additionally, this paper presents an advanced approach for RSA [iterative-randomized stimulation and averaging (I-RSA)], which includes the removal of the interference associated with overlapping responses through an iterative process in the time domain. Experimental results show that (a) RSA can be efficiently used in the recording of AEPs when the jitter of the stimulation sequence is greater than the dominant period of the AEP components, and (b) I-RSA maintains all the advantages of RSA and is not constrained by the restriction of a minimum jitter. The significance of the results of this study is discussed. 2025-01-21T11:52:01Z 2025-01-21T11:52:01Z 2014-12 journal article Valderrama JT, de la Torre A, Alvarez IM, Segura JC, Thornton ARD, Sainz M, Vargas JL. Auditory brainstem and middle latency responses recorded at fast rates with randomized stimulation. The Journal of the Acoustical Society of America (2014) 136, 3233-3248. doi: 10.1121/1.4900832 https://hdl.handle.net/10481/99838 10.1121/1.4900832 eng http://creativecommons.org/licenses/by-nc-nd/4.0/ open access Attribution-NonCommercial-NoDerivatives 4.0 Internacional Acoustical Society of America, AIP Publishing