Individual stress responses to Sarcoptes scabiei infestation in Iberian ibex, Capra pyrenaica Pérez, Jesús M. Molina, Lucía Ureña-Gutiérrez, Benjamín Espinosa, José López Montoya, Antonio Jesús Boos, Mathieu Granados, José E. Cano Manuel, Francisco J. Azorit, Concepción Capra pyrenaica Faecal 11-ketoetiocholanolone HPLC-MS/MS Individual stress response Non-invasive monitoring Sarcoptes scabiei In this study we have monitored the stress of Iberian ibex at individual level within the course of an experimental infection with Sarcoptes scabiei mites. For this purpose we have measured faecal 11-ketoetiocholanolone (11-k) using high-performance liquid chromatography coupled with tandem mass spectrometry (HPLC-MS/MS). We used linear mixed models to explore the effects of host sex and age, clinic (mange status) and time (number of days post-infection) on the concentration of faecal 11-k. The most parsimonious model included clinic, time and host age, which explained 76.6% of the variance of the response variable. Moreover, the concentration of faecal 11-k varied greatly between individuals. Our results evidence the stressor nature of the disease and highlight the negative effects on hosts due to cortisol release and activity. 2025-01-13T12:35:50Z 2025-01-13T12:35:50Z 2019 journal article Pérez, J. M., Molina, L., Ureña-Gutiérrez, B., Espinosa, J., López-Montoya, A. J., Boos, M., ... & Azorit, C. (2019). Individual stress responses to Sarcoptes scabiei infestation in Iberian ibex, Capra pyrenaica. General and Comparative Endocrinology, 281, 1-6. https://hdl.handle.net/10481/98992 https://doi.org/10.1016/j.ygcen.2019.05.007 eng http://creativecommons.org/licenses/by-nc-nd/4.0/ open access Attribution-NonCommercial-NoDerivatives 4.0 Internacional ELSEVIER