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      <dc:title>A multi-valent polymyxin-based fluorescent probe for the detection of Gram-negative infections†</dc:title>
      <dc:creator>Sharma, Richa</dc:creator>
      <dc:creator>Rodriguez Rios, Maria</dc:creator>
      <dc:creator>Crossland, James</dc:creator>
      <dc:creator>Septiyana, Maulida</dc:creator>
      <dc:creator>Megia-Fernandez, Alicia</dc:creator>
      <dc:creator>Klausen, Maxime</dc:creator>
      <dc:creator>Bradley, Mark</dc:creator>
      <dc:description>Amulti-branched fluorogenic probe for the rapid and specific detection of&#xd;
Gram-negative bacteria is reported. ThreeGram-negative-targeting azidomodified&#xd;
polymyxins were clicked onto a trivalent scaffold functionalised&#xd;
with the environmental green-emitting fluorophore 7-nitrobenz-2-oxa-&#xd;
1,3-diazole. The probe allowedwash-free detection of target bacteriawith&#xd;
increased sensitivity and lower limits of detection compared to monovalent&#xd;
probes.</dc:description>
      <dc:date>2025-01-07T11:43:51Z</dc:date>
      <dc:date>2025-01-07T11:43:51Z</dc:date>
      <dc:date>2024-12-17</dc:date>
      <dc:type>journal article</dc:type>
      <dc:identifier>Sharma, R. et. al.  J. Mater. Chem. B, 2025. [https://doi.org/10.1039/d4tb01786b]</dc:identifier>
      <dc:identifier>https://hdl.handle.net/10481/98502</dc:identifier>
      <dc:identifier>10.1039/d4tb01786b</dc:identifier>
      <dc:language>eng</dc:language>
      <dc:rights>http://creativecommons.org/licenses/by/4.0/</dc:rights>
      <dc:rights>open access</dc:rights>
      <dc:rights>Atribución 4.0 Internacional</dc:rights>
      <dc:publisher>Royal Society of Chemistry</dc:publisher>
   </ow:Publication>
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