Relationship between nutritional treatment compliance and nutritional status improvements in patients with gastrointestinal impairment taking an oral peptide based supplement Fernández Soto, María Luisa Objectives: Compliance in outpatients with gastrointestinal (GI) malabsorption is key in nutritional treatment. The objective of this study was to assess compliance in patients with GI impairment and malnutrition taking a high-calorie, high-protein, peptide-based oral nutritional supplement (ONS-PBD). Methods: A prospective, multicenter, observational study was conducted in 19 medical sites in Spain where ONS-PBD were prescribed as standard of care. Patients consumed ONS-PBD daily for 12 wk. Compliance was calculated as the percentage consumed of the prescribed amount of ONS per day. Results: A total of 90 adult patients were included in the study, of whom 64 completed the 12-wk regimine. Mean compliance was 78.8% § 24.5%. Risk of malnutrition decreased in 56.3% of patients at 12 wk, as measured with the malnutrition universal screening tool. A reduction in abdominal pain was observed and stool consistency improved, with a mean of 54.7% and 27.5%, respectively. Improvements in quality of life and a decrease in percentage of patients with severe functional impairment were observed. Conclusions: These data show that ONS-PBD compliance in malnourished patients with GI symptoms is high, reducing GI symptoms and improving patients’ nutritional status. 2024-12-16T07:35:57Z 2024-12-16T07:35:57Z 2022-05-04 journal article Jose A. Lopez-Medina MD, PHD a, Cristobal Lopez-Rodriguez b, María A. Estornell-Gualde MDc, Laura Rey-Fernández b, Silvia Gomez-Senent MDd, Clara Joaquín-Ortiz MDe, M. Luisa Fernández-Soto MDf, Roberto Hurtado-García MDg, Margarita Martín-Martín PHDh, Ana Barrera-Martín MSc, MDi, M. Teresa Vitales-Farrero j, Antonio J. Martínez-Ortega MD, PHDk, María Blanca-Martínez-Barbeito MDl, Bego~na Vazquez-Vizcaíno MDm, Clara Tasende-Fernandez MD, PHD n, M. Angeles Penacho-Lazaro MDo, Esther Jorda-Sorolla MDp, Rebeca Sanchez-Sanchez MDm, Laura Díaz-Gomez MDq, Sergio Baos-Fernandez r, German Guzman-Rolo MDs,*, María D. Ballesteros-Pomar MD, PHD. Nutrition 102 (2022) 111734.t https://hdl.handle.net/10481/98015 10.1016/j.nut.2022.111734 eng http://creativecommons.org/licenses/by-nc-nd/4.0/ open access Attribution-NonCommercial-NoDerivatives 4.0 Internacional Elsevier