Effects of interval aerobic training combined with strength exercise on body composition, glycaemic and lipid profile and aerobic capacity of obese rats Coll-Risco, Irene Aparicio García-Molina, Virginia Nebot, Elena Camiletti-Moirón, Daniel Martínez Martínez, Rosario Kapravelou, Garyfallia López-Jurado Romero De La Cruz, María Porres Foulquie, Jesús María Aranda Ramírez, Pilar This study was supported by the project DEP2011-04376 from the Ministry of Science and Innovation and grants from the Spanish Ministry of Education [grant number FPU13/01993], and is part of the PhD Thesis of Irene Coll Risco “Effects of an interval aerobic training combined with strength exercise and a diet on metabolic syndrome parameters on genetically obese rats”. VAA was also supported by the Andalucía Talent Hub Program launched by the Andalusian Knowledge Agency, co-funded by the European Union’s Seventh Framework Program, Marie Skłodowska-Curie actions (COFUND – [grant agreement number 291780]) and the Ministry of Economy, Innovation, Science and Employment of the Junta de Andalucía. The purpose of this study was to investigate the effects of interval aerobic training combined with strength exercise in the same training session on body composition, and glycaemic and lipid profile in obese rats. Sixteen lean Zucker rats and sixteen obese Zucker rats were randomly divided into exercise and sedentary subgroups (4 groups, n = 8). Exercise consisted of interval aerobic training combined with strength exercise in the same training session. The animals trained 60 min/day, 5 days/week for 8 weeks. Body composition, lipid and glycaemic profiles and inflammatory markers were assessed. Results showed that fat mass was reduced in both lean and obese rats following the exercise training (effect size (95% confidence interval (CI)) = 1.8 (0.5–3.0)). Plasma low-density lipoprotein–cholesterol and fasting glucose were lower in the exercise compared to the sedentary groups (d = 2.0 (0.7–3.2) and 1.8 (0.5–3.0), respectively). Plasma insulin was reduced in exercise compared to sedentary groups (d = 2.1 (0.8–3.4)). Some exercise × phenotype interactions showed that the highest decreases in insulin, homeostatic model assessment-insulin resistance, fasting and postprandial glucose were observed in the obese + exercise group (all, P < 0.01). The findings of this study suggest that interval aerobic training combined with strength exercise would improve body composition, and lipid and glycaemic profiles, especially in obese rats. 2024-11-08T12:18:13Z 2024-11-08T12:18:13Z 2016 journal article Coll-Risco, I., Aparicio, V. A., Nebot, E., Camiletti-Moirón, D., Martínez, R., Kapravelou, G., … Aranda, P. (2015). Effects of interval aerobic training combined with strength exercise on body composition, glycaemic and lipid profile and aerobic capacity of obese rats. Journal of Sports Sciences, 34(15), 1452–1460. https://doi.org/10.1080/02640414.2015.1119296 https://hdl.handle.net/10481/96771 10.1080/02640414.2015.1119296 eng http://creativecommons.org/licenses/by-nc-nd/3.0/ open access Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License Taylor & Francis