Association of physical fitness with health-related quality of life in early postmenopause Moratalla Cecilia, Natalia Soriano-Maldonado, Alberto Ruiz-Cabello, Pilar García-Fernández, M. M. Gregorio Arenas, Eva Aranda Ramírez, Pilar Aparicio García-Molina, Virginia Functional capacity Fitness testing Physical health Objective To assess the association of different components of physical fitness with HRQoL in early postmenopause and to test which physical fitness components are independently associated with the physical and mental components of HRQoL. Methods The final sample comprised 67 early postmenopausal women. Physical fitness was assessed with the Senior Fitness Test battery (additionally including handgrip strength test), and HRQoL was evaluated with the Short-Form Health Survey-36 (SF-36). We also analyzed plasma gonadotropic hormones and estradiol. Results Overall, most of the fitness components were positively associated with HRQoL. Lower-body flexibility, upper-body muscle strength and cardiorespiratory fitness were the fitness components more strongly associated with HRQoL (r range from 0.28 to 0.56). Static balance was especially associated with mental health (r = -0.46, P\0.001). Lower-body flexibility (assessed with the chair sit-and-reach test) and upper-body muscle strength (assessed with handgrip dynamometry) were independently associated with the SF-36 Physical Component Summary (both, P\0.001). Upper-body muscle strength (P\0.01) and cardiorespiratory fitness (assessed with the 6-min walk test, P\0.05) were independently associated with the SF- 36 Mental Component Summary. Conclusions Higher physical fitness is associated with better HRQoL in early postmenopause. Lower-body flexibility and upper-body muscle strength were the most important independent fitness indicators, explaining *30 % of HRQoL. 2024-10-17T07:48:47Z 2024-10-17T07:48:47Z 2016-10 journal article Moratalla Cecilia, N. et. al. Qual Life Res 25, 2675–2681 (2016). [https://doi.org/10.1007/s11136-016-1294-6] https://hdl.handle.net/10481/96046 10.1007/s11136-016-1294-6 eng info:eu-repo/grantAgreement/EC/FP7/291780 http://creativecommons.org/licenses/by/4.0/ open access Atribución 4.0 Internacional Springer