Nutrimetabolomics: An Update on Analytical Approaches to Investigate the Role of Plant-Based Foods and Their Bioactive Compounds in Non-Communicable Chronic Diseases Rangel Huerta, Óscar Daniel Gil Hernández, Ángel Bioactive compounds Metabolomics Non-communicable chronic diseases Metabolomics is the study of low-weight molecules present in biological samples such as biofluids, tissue/cellular extracts, and culture media. Metabolomics research is increasing, and at the moment, it has several applications in the food science and nutrition fields. In the present review, we provide an update about the most frequently used methodologies and metabolomic platforms in these areas. Also, we discuss different metabolomic strategies regarding the discovery of new bioactive compounds (BACs) in plant-based foods. Furthermore, we review the existing literature related to the use of metabolomics to investigate the potential protective role of BACs in the prevention and treatment of non-communicable chronic diseases, namely cardiovascular disease, diabetes, and cancer. 2024-10-01T07:16:05Z 2024-10-01T07:16:05Z 2016-12-09 journal article Rangel-Huerta, O.D.; Gil, A. Nutrimetabolomics: An Update on Analytical Approaches to Investigate the Role of Plant-Based Foods and Their Bioactive Compounds in Non-Communicable Chronic Diseases. Int. J. Mol. Sci. 2016, 17, 2072. https://doi.org/10.3390/ijms17122072 https://hdl.handle.net/10481/95293 10.3390/ijms17122072 eng http://creativecommons.org/licenses/by/4.0/ open access Atribución 4.0 Internacional MDPI