<rdf:RDF xmlns:rdf="http://www.openarchives.org/OAI/2.0/rdf/" xmlns:ow="http://www.ontoweb.org/ontology/1#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:ds="http://dspace.org/ds/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:doc="http://www.lyncode.com/xoai" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/rdf/ http://www.openarchives.org/OAI/2.0/rdf.xsd">
   <ow:Publication rdf:about="oai:digibug.ugr.es:10481/94134">
      <dc:title>Comparison of the influence of alcohol and cannabis on the dynamics of the accommodative response</dc:title>
      <dc:creator>Casares López, Miriam</dc:creator>
      <dc:creator>Ortiz Peregrina, Sonia</dc:creator>
      <dc:creator>Ortiz Herrera, Carolina</dc:creator>
      <dc:creator>Castro Torres, José Juan</dc:creator>
      <dc:creator>González Anera, Rosario</dc:creator>
      <dc:subject>Accommodation dynamics</dc:subject>
      <dc:subject>Accommodative lag</dc:subject>
      <dc:subject>Accommodative response</dc:subject>
      <dc:subject>Alcohol consumption</dc:subject>
      <dc:subject>Cannabis use</dc:subject>
      <dc:description>Purpose: to assess and compare the changes produced by the two most commonly used substances, alcohol and cannabis, on accommodation dynamics. &#xd;
Methods: A total of 38 young participants (19 females) were enrolled in the study. They were assigned to two groups: a cannabis group (N = 19) and an alcohol group. Participants in the cannabis group underwent two randomized sessions: a baseline session and a session after smoking a cigarette. Participants in the alcohol group underwent three randomized sessions: a baseline session, a session after the intake of 300 ml of red wine (Alcohol 1), and other after the ingestion of 450 ml of wine (Alcohol 2). For the accommodation assessment, the open-field autorefractor WAM-5500 was used. &#xd;
Results: The decrease of the mean velocity of the accommodative response produced by Alcohol 2 condition was significantly greater than that observed for Alcohol 1 and Cannabis (p = 0.046). The direction of the accommodation (near-distance and distance-near) had no effect on the deterioration of the accommodation dynamics following substance use. The target distance had a significant effect on the decrease of the mean velocity following substance use (p = 0.002). The decrease of the amplitude of the accommodative response was associated with a decrease of the peak velocity (p = 0.004) and the increase of the accommodative lag (p &lt; 0.001).&#xd;
Conclusions: a moderate-high dose of alcohol impairs accommodation dynamics to a greater extent that lower dose of alcohol or smoked cannabis. The deterioration of the accommodation mean speed was higher for a shorter target distance.</dc:description>
      <dc:date>2024-09-09T07:12:31Z</dc:date>
      <dc:date>2024-09-09T07:12:31Z</dc:date>
      <dc:date>2023-03-28</dc:date>
      <dc:type>journal article</dc:type>
      <dc:identifier>Casares-López M, Ortiz-Peregrina S, Ortiz C, Castro-Torres JJ, Anera RG. Comparison of the influence of alcohol and cannabis on the dynamics of the accommodative response. Graefes Arch Clin Exp Ophthalmol 261(8):2281-2289 (2023))</dc:identifier>
      <dc:identifier>https://hdl.handle.net/10481/94134</dc:identifier>
      <dc:identifier>10.1007/s00417-023-06020-5</dc:identifier>
      <dc:language>eng</dc:language>
      <dc:rights>http://creativecommons.org/licenses/by-nc/4.0/</dc:rights>
      <dc:rights>open access</dc:rights>
      <dc:rights>Atribución-NoComercial 4.0 Internacional</dc:rights>
      <dc:publisher>Springer</dc:publisher>
   </ow:Publication>
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