Relationship between the duration of the clinical course of human brucellosis and the avidity of specific IgG antibodies Gutiérrez Fernández, José Rodríguez, M. Maroto, M.C. The aim of this work was to relate the avidity of specific IgG antibodies with the time of evolution of human brucella infection. IgG anti-brucella antibodies were measured using an ELISA assay with 8 M urea in 17 patients with recent active brucellosis (group I), 31 patients with chronic active brucellosis (group II) and 120 asymptomatic patients with past brucellosis (group III). Twelve patients of group I (70.6%), three of group II (9.7%) and none in group III had low avidity antibodies against Brucella. It is concluded that these antibodies have a high diagnostic efficiency for recent Brucella infections. 2024-06-04T08:24:30Z 2024-06-04T08:24:30Z 1995-07 info:eu-repo/semantics/article Gutiérrez J, Rodríguez M, Maroto MC. Relación entre el tiempo de evolución de la brucelosis humana y la avidez de anticuerpos IgG específicos [Relationship between the duration of the clinical course of human brucellosis and the avidity of specific IgG antibodies]. Rev Med Chil. 1995 Jul;123(7):819-22. Spanish. PMID: 8560111 https://hdl.handle.net/10481/92300 spa http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess Attribution-NonCommercial-NoDerivatives 4.0 Internacional Rev Med Chil .