Feasibility, Clinical Efficacy, and Maternal Outcomes of a Remote Exercise Program in Pregnant Women with Obesity: The GROB Randomized Control Pilot Study Bernardo, Diana Bobadilla Agouborde, Carolina Festas, Clarinda Carvalho, Carlos Abdalla, Pedro Pugliesi Amezcua Prieto, María Del Carmen Naia Entonado, Zeltia Mesquita, Cristina Carvalho Mota, Jorge Santos, Paula Clara Pregnancy Exercise Physical activity Obesity Background: Obesity is common in women of reproductive age and increases the risk during pregnancy. Exercising during this period reduces health complications. Home e-health programs are effective in overcoming exercise barriers as pregnant women use technology and the internet for health information. Methods: A single-blind randomized controlled feasibility study with pregnant women with obesity (body mass index [BMI] ≥30 kg/m2) was conducted in the University Hospital Center of São João between January and April 2023. Pregnant women were randomized to a control group with standard care and to an experimental group with 8-week remote exercise program using a Phoenix® biofeedback device. Feasibility outcome measures were recruitment rate (≥35%), loss to follow-up (≤15%), and program fidelity (≥1 session/week). Secondary outcomes were evaluated through Pregnancy Physical Activity Questionnaire, Oswestry Index on Disability, and weight assessments at baseline and at the end of the program. Results: Of the 63 eligible participants, 24 (38.1%) were successfully randomized and completed the baseline assessment. Of these, 3 (4.8%) from experimental group did not perform the initial onboarding. The control group had 8.3% of follow-up losses and for the experimental group there were no follow-up losses. Program fidelity (mean ≥1 session/week) was fulfilled by 66.7% of successfully randomized participants. Regarding secondary outcomes assessed between baseline and the 8th week, experimental group compared to control group had higher levels of physical activity for sports activities, a lower level of inactivity, and lower disability rates caused by low back pain. Conclusions: Based on the recruitment rate, losses to follow-up, and fidelity rate, the GROB (obesity in pregnancy) study was deemed feasible and worthy of consideration for a larger study. Moreover, the GROB study has the potential to improve maternal outcomes by reducing sedentarism and disability caused by low back pain. Clinical Trial Registration: The study has been registered on https://classic.clinicaltrials.gov/ (registration number: NCT05331586). 2024-05-22T11:23:12Z 2024-05-22T11:23:12Z 2024-03-15 journal article Diana Bernardo, Carolina Bobadilla-Agouborde, Clarinda Festas, Carlos Carvalho, Pedro Pugliesi Abdalla, Carmen Amezcua-Prieto, Zeltia Naia-Entonado, Cristina Carvalho Mesquita, Jorge Mota, Paula Clara Santos. Feasibility, Clinical Efficacy, and Maternal Outcomes of a Remote Exercise Program in Pregnant Women with Obesity: The GROB Randomized Control Pilot Study. Clin. Exp. Obstet. Gynecol. 2024, 51(3), 70. https://doi.org/10.31083/j.ceog5103070 https://hdl.handle.net/10481/91985 10.31083/j.ceog5103070 eng http://creativecommons.org/licenses/by/4.0/ open access Atribución 4.0 Internacional IMR Press