A comparison of two ELISA methods for the investigation of anti-cytomegalovirus IgG antibodies Gutiérrez Fernández, José Maroto Vela, María del Carmen IgG antibodies Serodiagnosis Cytomegalovirus The Alpha-method ELISA for detection of anti-cytomegalovirus (CMV) IgG antibodies (test 1) was compared with another ELISA technique MEIA (test 2). Samples (248 sera and 56 cerebrospinal fluid) from patients with suspected CMV infection were investigated. Discordant samples were re-analysed, undiluted, with a latex test. Positive results were considered to be true positives when there was agreement in the results from the two methods. There were fourteen discrepant samples (4.6%). The latex agglutination test confirmed eight positive for test 1 and six positive for test 2. The overall diagnostic yield of tests 1 and 2 was sensitivity, 91% and 100%; specificity, 99% and 96%; positive predictive values, 95% and 85%; and negative predictive values 98% and 100%, respectively. 2024-04-25T09:29:05Z 2024-04-25T09:29:05Z 1997-02 info:eu-repo/semantics/article Gutiérrez J, Maroto MC. A comparison of two ELISA methods for the investigation of anti-cytomegalovirus IgG antibodies. Microbios. 1997;90(364-365):151-4. PMID: 9418034 https://hdl.handle.net/10481/91148 eng http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess Attribution-NonCommercial-NoDerivatives 4.0 Internacional Faculty Press