32-week premature rupture of membranes caused by oropharyngeal microbiota Hidalgo-Chicharro, Alberto Abad-Torreblanca, Raquel Navarro-Marí, José María Gutiérrez Fernández, José Premature rupture of membranes Molecular characterization Staphylococcus aureus Neisseria meningitidis Haemophilus influenzae Preventive antibiotic therapy Introduction. Preterm premature rupture of membranes (PPROM) usually has a multifactorial etiology that is often unknown, although the most frequently reported cause is infection by group B Streptococcus. Therefore, the etiology of PPROM, although probably infectious, remains unknown in most cases. This case describes a PPROM caused by infection from oropharyngeal microbiota. Case presentation. We report the case of a 26-yr-old pregnant woman. The gestational age was 32 weeks+5 days. Examinations in the emergency department revealed the release of clear amniotic fluid and a closed multiparous cervix with a length of 22 mm. Endocervical culture evidenced the growth of Staphylococcus aureus, serogroup B Neisseria meningitidis and Haemophilus influenzae. Conclusion. Preventive antibiotic therapy should consider: opportunistic infections by normal genital microbiota, infections due to sexual activity, opportunist microorganisms derived from oral sex, and the hematogenous spread of oral bacteria. 2024-04-25T09:06:44Z 2024-04-25T09:06:44Z 2017-10 journal article Hidalgo-Chicharro et al. 32-week premature rupture of membranes caused by oropharyngeal microbiota. JMM Case Reports 2017;4. DOI 10.1099/jmmcr.0.005121 https://hdl.handle.net/10481/91145 10.1099/jmmcr.0.005121 eng http://creativecommons.org/licenses/by-nc-nd/4.0/ open access Attribution-NonCommercial-NoDerivatives 4.0 Internacional Microbiology Society