Vasodilatory Peripheral Response and Pain Levels following Radiofrequency Stressor Application in Women with Fibromyalgia Casas Barragán, Antonio Muñoz Revilla, Alba Tapia Haro, Rosa María Molina Ortega, Francisco Javier Correa Rodríguez, María Aguilar Ferrandiz, María Encarnación Fibromyalgia Radiofrequency Peripheral temperature Fibromyalgia (FM) is a syndrome of unknown pathogenesis that presents, among other symptoms, chronic widespread musculoskeletal pain. This study aims to analyze the effects of radiofrequency on core body temperature and the peripheral temperature of the dorsal surfaces and palms of the hands and its association with pain levels in patients with FM. A case-control observational study was conducted with a total of twenty-nine women diagnosed with FM and seventeen healthy women. Capacitive monopolar radiofrequency was applied to the palms of the hands using the Biotronic Advance Develops device. Peripheral hand temperature was analyzed using a thermographic camera, and core body temperature was analyzed with an infrared scanner. Pressure pain thresholds (PPTs) and electrical pain were recorded with an algometer and a Pain Matcher device, respectively. A significant decrease was observed in women with FM in pain electrical threshold (95% CI [0.01–3.56], p = 0.049), electrical pain (95% CI [2.87–10.43], p = 0.002), dominant supraspinatus PPT (95% CI [0.04–0.52], p = 0.023), non-dominant supraspinatus PPT (95% CI [0.03–0.60], p = 0.029), and non-dominant tibial PPT (95% CI [0.05–0.89], p = 0.031). Women with FM have increased hypersensitivity to pain as well as increased peripheral temperature after exposure to a thermal stimulus, such as radiofrequency, which could indicate disorders of their neurovascular response. 2024-04-17T10:46:27Z 2024-04-17T10:46:27Z 2024-01-10 journal article Casas-Barragán, A.; Muñoz-Revilla, A.; Tapia-Haro, R.M.; Molina, F.; Correa-Rodríguez, M.; Aguilar-Ferrándiz, M.E. Vasodilatory Peripheral Response and Pain Levels following Radiofrequency Stressor Application inWomen with Fibromyalgia. Biomedicines 2024, 12, 142. https://doi.org/10.3390/biomedicines12010142 https://hdl.handle.net/10481/90832 10.3390/biomedicines12010142 eng http://creativecommons.org/licenses/by/4.0/ open access Atribución 4.0 Internacional MDPI