Resting heart rate but not heart rate variability is associated with the normal-weight obesity phenotype Plaza Florido, Abel Adrián Ruiz Ruiz, Jonatan Alcántara Alcántara, Juan Manuel Objective: To determine differences in resting heart rate variability (HRV) and heart rate (HR) between young adults with normal-weight obesity (NWO) and normal-weight lean (NWL). Methods: A total of 65 normal-weight individuals (18–25 years old, 50 women, body mass index 18.5 to 24.9 kg/m2) were included in this cross-sectional study. Body fat percentage was determined using a whole-body dual energy x-ray absorptiometry scanner. Resting HRV and HR were assessed with the Polar RS800CX. Forty-one participants were classified as NWO and 24 NWL using cutoff points for body fat percentage (33.3% for women and 23.1% for men). Results: There were no differences in HRV between NWO and NWL groups (all p > .05). HR was higher in NWO (mean 70 beats per minute [bpm], standard deviation [SD] 8) than in NWL adults (mean 65 bpm, SD 10), the adjusted mean difference 5 bpm (95% CI, 0 to 10 bpm). Conclusion: HR is a noninvasive biomarker and relatively cheap, fast, and easy to measure that could detect “apparently healthy” young individuals with an adverse cardiovascular disease risk profile despite presenting a normal body weight. 2024-04-16T10:35:25Z 2024-04-16T10:35:25Z 2024-01-26 journal article Plaza-Florido, A., Ruiz, J. R., & Alcantara, J. M. A. (2024). Resting heart rate but not heart rate variability is associated with the normal-weight obesity phenotype. American Journal of Human Biology, e24043. https://doi.org/10.1002/ajhb.24043 https://hdl.handle.net/10481/90783 10.1002/ajhb.24043 eng info:eu-repo/grantAgreement/EC/NextGenerationEU/FJC2020-044453-I http://creativecommons.org/licenses/by/4.0/ open access Atribución 4.0 Internacional Wiley-VCH GmbH