Clinical utility of a competitive ELISA to detect antibodies against Treponema pallidum Gutiérrez Fernández, José Vergara, M.J. Soto, M.J. Piédrola Angulo, Gonzalo Maroto, M.D. Screening for Treponema pallidum infection is carried out on a large human population. To reduce costs, fewer tests which still offer adequate sensitivity and specificity could be performed. We studied the reliability of a novel indirect ELISA method to test for this infection. Several panels of sera were used that corresponded to 40 primary infections (group 1), 13 recurrences (group 2), 348 latent infections (group 3), 5 samples with anticardiolipin antibodies (group 4), 15 samples from patients with Lyme borreliosis (group 5), and 400 samples from blood donors and healthy pregnant women (group 6). The ELISA showed a global sensitivity and specificity of 100 and 99.5%, respectively. Our evaluation shows that Enzygnost Syphilis is a sensitive, specific, and simple test to screen for this infection. 2024-03-19T08:21:49Z 2024-03-19T08:21:49Z 2000 info:eu-repo/semantics/article Gutiérrez J, Vergara MJ, Soto MJ, Piédrola G, Maroto Md. Clinical utility of a competitive ELISA to detect antibodies against Treponema pallidum. J Clin Lab Anal. 2000;14(2):83-6. https://hdl.handle.net/10481/90098 10.1002/(SICI)1098-2825(2000)14:2<83::AID-JCLA8>3.0.CO;2-A eng http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess Attribution-NonCommercial-NoDerivatives 4.0 Internacional J Clin Lab Anal .