Behaviour of IgG antibody avidity for the antigen and of IgA antibody in active cytomegalovirus, Epstein-Barr virus, herpes simplex virus and human herpes virus 6 infections. Adaptation of a commercial test Gutiérrez Fernández, José Rodríguez, M. Maroto Vela, María del Carmen Piédrola Angulo, Gonzalo Peirón, J. The clinical value of specific IgA and IgG antibody avidity to herpes simplex virus, cytomegalovirus, Epstein-Barr virus and human herpes virus 6 for the detection of active disease and primary infection, respectively, was evaluated. The IgG avidity test, with a break point of 55%, for the detection of primary infection, and of the IgA test for the detection of disease, were associated with a sensitivity of 97% and 64%, respectively; specificity of 100% and 82%; a positive predictive value of 100% and 76%; and a negative predictive value of 96% and 72%, respectively. 2024-03-18T12:23:37Z 2024-03-18T12:23:37Z 1997-07 info:eu-repo/semantics/article Gutiérrez J, Rodríguez M, Maroto MC, Piédrola G, Peirón J. Behaviour of IgG antibody avidity for the antigen and of IgA antibody in active cytomegalovirus, Epstein-Barr virus, herpes simplex virus and human herpes virus 6 infections. Adaptation of a commercial test. J Infect. 1997 Jul;35(1):25-30. https://doi.org/10.1016/S0163-4453(97)90881-1 https://hdl.handle.net/10481/90083 10.1016/s0163-4453(97)90881-1 eng http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess Attribution-NonCommercial-NoDerivatives 4.0 Internacional Elsevier