Diagnosis of leishmaniasis Gutiérrez Fernández, José Elmahallawy, Ehab Kotb Sampedro Martinez, Antonio Rodriguez-Granger, Javier Hoyos-Mallecot, Yannick Agil, Ahamd Navarro Mari, Jose Mari Leishmaniasis is a clinically heterogeneous syndrome caused by intracellular protozoan parasites of the genus Leishmania. The clinical spectrum of leishmaniasis encompasses subclinical (not apparent), localized (skin lesion), and disseminated (cutaneous, mucocutaneous, and visceral) infection. This spectrum of manifestations depends on the immune status of the host, on the parasite, and on immunoinflammatory responses. Visceral leishmaniasis causes high morbidity and mortality in the developing world. Reliable laboratory methods become mandatory for accurate diagnosis, especially in immunocompromised patients such as those infected with HIV. In this article, we review the current state of the diagnostic tools for leishmaniasis, especially the serological test. 2024-03-11T12:12:10Z 2024-03-11T12:12:10Z 2014-08 journal article Elmahallawy EK, Sampedro Martinez A, Rodriguez-Granger J, Hoyos-Mallecot Y, Agil A, Navarro Mari JM, Gutierrez Fernandez J. Diagnosis of leishmaniasis. J Infect Dev Ctries. 2014 Aug 13;8(8):961-72. https://hdl.handle.net/10481/89921 10.3855/jidc.4310 eng http://creativecommons.org/licenses/by-nc-nd/4.0/ open access Attribution-NonCommercial-NoDerivatives 4.0 Internacional J Infect Dev Ctries