Cation Exchange Strategy for the Encapsulation of a Photoactive COReleasing Organometallic Molecule into Anionic Porous Frameworks Carmona Fernández, Francisco Jesús Rodríguez Maldonado, Carmen Barea Martínez, Elisa María Rojas Macías, Sara Sánchez Sánchez, Purificación Marques, Ana. R Romão, Carlos C. Jeremias, Hélia Choquesillo Lazarte, Duane Rodríguez Navarro, Jorge Andrés The encapsulation of the photoactive, nontoxic, water-soluble, and air-stable cationic CORM [Mn(tacn)(CO)3]Br (tacn = 1,4,7-triazacyclononane) in different inorganic porous matrixes, namely, the metalorganic framework bio-MOF-1, (NH2(CH3)2)2[Zn8(adeninate)4(BPDC)6]·8DMF·11H2O (BPDC = 4,4′-biphenyldicarboxylate), and the functionalized mesoporous silicas MCM-41-SO3H and SBA-15-SO3H, is achieved by a cation exchange strategy. The CO release from these loaded materials, under simulated physiological conditions, is triggered by visible light. The results show that the silica matrixes, which are unaltered under physiological conditions, slow the kinetics of CO release, allowing a more controlled CO supply. In contrast, bio-MOF-1 instability leads to the complete leaching of the CORM. Nevertheless, the degradation of the MOF matrix gives rise to an enhanced CO release rate, which is related to the presence of free adenine in the solution. 2024-02-02T13:03:02Z 2024-02-02T13:03:02Z 2016-06-11 journal article Inorg. Chem. 2016, 55, 13, 6525–6531 https://hdl.handle.net/10481/88036 https://doi.org/10.1021/acs.inorgchem.6b00674 eng open access ACS