Limitations in Activities of Daily Living Among Spanish Women Diagnosed With Endometriosis Lozano-Lozano, Mario Mundo López, Antonio San-Sebastian, Ainhoa P Galiano-Castillo, Noelia Fernández-Lao, Carolina Cantarero-Villanueva, Irene Arroyo-Morales, Manuel Ocón Hernández, Olga Artacho Cordón, Francisco Endometriosis Pain Fatigue catastrophization Importance: Understanding the impact of endometriosis symptoms on patients' activities of daily living (ADLs) is a priority to establish effective and personalized intervention programs. Objective: To explore limitations in ADLs and instrumental ADLs (IADLs) and their association with pelvic pain (PP), chronic fatigue, and pain-catastrophizing thoughts among women with endometriosis. Design: Cross-sectional study. Setting: Spain. Participants: Two hundred thirty women with endometriosis. Outcomes and Measures: Information regarding performance of ADLs (Barthel Index) and IADLs (Lawton-Brody questionnaire), PP intensity (Numeric Rating Scale), chronic fatigue (Piper Fatigue Scale), and pain-catastrophizing thoughts (Pain Catastrophizing Scale) was gathered. Multivariate regression analyses were created, and mediating effects of fatigue and pain-catastrophizing thoughts on the association between PP and ADL and IADL limitations were assessed. Results: The prevalence of limitations in at least one ADL and one IADL was 22.6% (95% confidence interval [CI] [17.2, 28.1]) and 39.1% (95% CI [32.8, 45.5]), respectively. Limitations in bowel continence, housework, shopping, and meal preparation were reported most frequently. Women reporting severe PP showed higher risk for ADL (odds ratio [OR] = 3.33, 95% CI [1.10, 10.10]) and IADL (OR = 7.99, 95% CI [2.86, 22.34]) limitations. Chronic fatigue and pain-catastrophizing thoughts were also positively related to ADL-IADL limitations, showing a mediating effect on the association between PP and ADL-IADL limitations. Conclusions and relevance: This study reveals the widespread presence of difficulties in ADL-IADL performance among women with endometriosis, with some symptoms underlying these difficulties in occupational performance. This study points to the need for cost-effective occupational therapy interventions for affected women. What This Article Adds: This research shows that the occupational performance of women with endometriosis is frequently impaired; therefore, the effectiveness of occupational therapy interventions should be addressed in the near future. 2024-01-30T11:01:06Z 2024-01-30T11:01:06Z 2021-11-29 journal article Lozano-Lozano, M., Mundo-López, A., San-Sebastian, A. P., Galiano-Castillo, N., Fernandez-Lao, C., Cantarero-Villanueva, I., Arroyo-Morales, M., Ocón-Hernández, O., & Artacho-Cordón, F. (2021). Limitations in Activities of Daily Living Among Spanish Women Diagnosed With Endometriosis. The American journal of occupational therapy : official publication of the American Occupational Therapy Association, 75(6), 7506205050. https://doi.org/10.5014/ajot.2021.044974 https://hdl.handle.net/10481/87620 10.5014/ajot.2021.044974 eng The American Journal of Occupational Therapy;75(6) open access