Taste learning and memory: a window on the study of brain aging Gámiz Ruiz, Fernando Gallo Torre, Milagros Aging Context Hippocampus Learning Memory Taste Rat Supported by the research projects HUM 02763 (Junta de Andalucía. Spain), PSIC2008-03933 (MICINN. Spain), PSI2011-23702 (MICINN. Spain), and FPU fellowship to Fernando Gámiz (MICINN, Spain). Taste aversion learning exhibits advantages for research on memory brain systems and its reorganization throughout life. A review of the effects of aging on taste memory abilities offers a complex picture showing preserved, impaired, and enhanced functions. Some of the age-related changes in taste memory seem to be associated with an altered temporal processing. Longer tasteillness delays can be introduced for acquisition of conditioned taste aversions and the modulation of taste learning by the temporal context is absent in naive old rats. It is suggested that an altered hippocampal function is involved in the peculiar performance of these rats. Evidence is also presented which suggests that hippocampal-dependent taste memory can be reactivated by previous learning experiences in old rats. Results obtained after reversible inactivation of the dorsal Hippocampus by tetrodotoxin (TTX) in old rats support such a view. Therefore, the interaction between the previous experience and acute brain interventions should be taken into account when studying the effect of aging on taste memory 2024-01-12T09:47:49Z 2024-01-12T09:47:49Z 2011-11-08 journal article Gámiz and Gallo. Taste learning and memory: a window on the study of brain aging. Front. Syst. Neurosci. 5 - 2011. [https://doi.org/10.3389/fnsys.2011.00091] https://hdl.handle.net/10481/86746 10.3389/fnsys.2011.00091 eng http://creativecommons.org/licenses/by-nc-nd/4.0/ open access Attribution-NonCommercial-NoDerivatives 4.0 Internacional Frontiers Media