Advances and challenges in Bioinformatics and Biomedical Engineering: IWBBIO 2020 Valenzuela Cansino, Olga Rojas Ruiz, Ignacio High performance in Bioinformatics Next generation sequencing and sequence analysis Biomedicine Biomedical engineering Computational systems for modelling biological processes Healthcare and diseases This Supplement issue, presents five research articles which are distributed, mainly due to the subject they address, from the 8th International Work-Conference on Bioinformatics and Biomedical Engineering (IWBBIO 2020), which was held on line, during September, 30th–2nd October, 2020. These contributions have been chosen because of their quality and the importance of their findings. Those contributions were then invited to participate in this supplement for the following journals of BMC: BMC Bioinformatics and BMC Genomics. In the present Editorial in BMC journal, we summarize the contributions that provide a clear overview of the thematic areas covered by the IWBBIO conference, ranging from theoretical/review aspects to real-world applications of bioinformatic and biomedical engineering 2023-11-13T09:32:57Z 2023-11-13T09:32:57Z 2023-10-18 journal article Valenzuela, O., Cannataro, M., Rusur, I. et al. Advances and challenges in Bioinformatics and Biomedical Engineering: IWBBIO 2020. BMC Bioinformatics 24 (Suppl 2), 361 (2023). [https://doi.org/10.1186/s12859-023-05448-0] https://hdl.handle.net/10481/85610 10.1186/s12859-023-05448-0 eng http://creativecommons.org/licenses/by/4.0/ open access Atribución 4.0 Internacional Springer Nature