Antibacterial Cu or Zn-MOFs Based on the 1,3,5-Tris-(styryl)benzene Tricarboxylate Lelouche, Sorraya Najma Kinza Rodríguez Diéguez, Antonio Metal-organic frameworks Antibacterial activity Oligo(styryl)benzenes This work was funded by the Marie Skłodowska-Curie Actions, HeatNMof ITN under Grant ID: 860942, Marie Sklodowska-Curie grant agreement No. 101061833 (BioPolyMOF). Universidad de Castilla-La Mancha project 2022-GRIN-34214. Supplementary Materials: The following supporting information can be downloaded at: https: //www.mdpi.com/article/10.3390/nano13162294/s1 Metal–organic frameworks (MOFs) are highly versatile materials. Here, two novel MOFs, branded as IEF-23 and IEF-24 and based on an antibacterial tricarboxylate linker and zinc or copper cations, and holding antibacterial properties, are presented. The materials were synthesized by the solvothermal route and fully characterized. The antibacterial activity of IEF-23 and IEF-24 was investigated against Staphylococcus epidermidis and Escherichia coli via the agar diffusion method. These bacteria are some of the most broadly propagated pathogens and are more prone to the development of antibacterial resistance. As such, they represent an archetype to evaluate the efficiency of novel antibacterial treatments. MOFs were active against both strains, exhibiting higher activity against Staphylococcus epidermidis. Thus, the potential of the developed MOFs as antibacterial agents was proved. 2023-10-05T11:02:35Z 2023-10-05T11:02:35Z 2023-08-09 journal article Lelouche, S.N.K.; Albentosa-González, L.; Clemente-Casares, P.; Biglione, C.; Rodríguez-Diéguez, A.; Tolosa Barrilero, J.; García-Martínez, J.C.; Horcajada, P. Antibacterial Cu or Zn-MOFs Based on the 1,3,5-Tris-(styryl)benzene Tricarboxylate. Nanomaterials 2023, 13, 2294. [https://doi.org/10.3390/nano13162294] https://hdl.handle.net/10481/84860 10.3390/nano13162294 eng info:eu-repo/grantAgreement/EC/H2020/101061833 info:eu-repo/grantAgreement/EC/H2020/860942 http://creativecommons.org/licenses/by/4.0/ open access Atribución 4.0 Internacional MDPI