Adaptive coding of stimulus information in human frontoparietal cortex during visual classification Wisniewski, David González García, Carlos Formica, Silvia Woolgar, Alexandra Brass, Marcel fMRI RSA Frontoparietal cortex Multiple demand Perceptual classification DW was supported by the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie grant agreement no. 665501, the Flemish Science Foundation (FWO, FWO.KAN.2019.0023.01), and the Special Research Fund of Ghent University. CGG was supported by the Spanish Ministry of Science and Innovation (IJC2019–040208-I). SF was supported by the Einstein Foundation Berlin. AW was supported by Medical Research Council (U.K) intramural funding SUAG/052/G101400. MB was supported by an Einstein Strategic Professorship of the Einstein Foundation Berlin, and a GOA of the Special Research Fund of Ghent University (BOF.GOA.2017.0002.03) The neural mechanisms of how frontal and parietal brain regions support flexible adaptation of behavior remain poorly understood. Here, we used functional magnetic resonance imaging (fMRI) and representational similarity analysis (RSA) to investigate frontoparietal representations of stimulus information during visual classification under varying task demands. Based on prior research, we predicted that increasing perceptual task difficulty should lead to adaptive changes in stimulus coding: task-relevant category information should be stronger, while task-irrelevant exemplar-level stimulus information should become weaker, reflecting a focus on the behaviorally relevant category information. Counter to our expectations, however, we found no evidence for adaptive changes in category coding. We did find weakened coding at the exemplar-level within categories however, demonstrating that task-irrelevant information is de-emphasized in frontoparietal cortex. These findings reveal adaptive coding of stimulus information at the exemplar-level, highlighting how frontoparietal regions might support behavior even under challenging conditions. 2023-07-19T07:52:58Z 2023-07-19T07:52:58Z 2023-07-01 journal article D. Wisniewski, C. González-García, S. Formica et al. Adaptive coding of stimulus information in human frontoparietal cortex during visual classification. NeuroImage 274 (2023) 120150. [https://doi.org/10.1016/j.neuroimage.2023.120150] https://hdl.handle.net/10481/83855 10.1016/j.neuroimage.2023.120150 eng info:eu-repo/grantAgreement/EC/H2020/665501 http://creativecommons.org/licenses/by-nc-nd/4.0/ open access Attribution-NonCommercial-NoDerivatives 4.0 Internacional Elsevier