Characteristics of Frailty in Perimenopausal Women with Long COVID-19 Navas-Otero, Alba Calvache Mateo, Andrés Martín-Núñez, Javier Calles Plata, Irene Ortiz Rubio, Araceli Valenza, Marie Carmen López López, Laura Disability Frailty Long COVID-19 syndrome Perimenopausal women The aim of this study was to compare the prevalence of risk factors for frailty between perimenopausal women with long COVID-19 syndrome, women having successfully recovered from COVID-19, and controls from the community. Women with a diagnosis of long COVID-19 and at least one symptom related to the perimenopausal period, women who had successfully recovered from COVID-19, and healthy women of comparable age were included in this study. Symptom severity and functional disability were assessed with the COVID-19 Yorkshire Rehabilitation Scale, and the presence of frailty was evaluated considering the Fried criteria. A total of 195 women were included in the study, distributed over the three groups. The long COVID-19 group showed a higher prevalence of perimenopausal symptoms and impact of COVID-19. Statistically significant differences were found between the long COVID-19 group and the other two groups for the frailty variables. When studying the associations between frailty variables and COVID-19 symptom impact, significant positive correlations were found. Perimenopausal women with long COVID-19 syndrome present more frailty-related factors and experience a higher range of debilitating ongoing symptoms. A significant relationship is shown to exist between long COVID-19 syndrome-related disability and symptoms and frailty variables, resulting in an increased chance of presenting disability. 2023-06-26T09:59:47Z 2023-06-26T09:59:47Z 2023-05-18 journal article Navas-Otero, A.; Calvache-Mateo, A.; Martín-Núñez, J.; Calles-Plata, I.; Ortiz-Rubio, A.; Valenza, M.C.; López, L.L. Characteristics of Frailty in PerimenopausalWomen with Long COVID-19. Healthcare 2023, 11, 1468. [https://doi.org/10.3390/healthcare11101468] https://hdl.handle.net/10481/82812 10.3390/healthcare11101468 eng http://creativecommons.org/licenses/by/4.0/ open access Atribución 4.0 Internacional MDPI