A transcranial magnetic stimulation study on the role of the left intraparietal sulcus in temporal orienting of attention Capizzi, Mariagrazia Martín Signes, Mar Coull, Jennifer T. Chica Martínez, Ana Belén Charras, Pom Endogenous attention Time Foreperiod Diffusion-weighted imaging Superior longitudinal fasciculus likely to occur. Temporal orienting of attention has been consistently associated with activation of the left intraparietal sulcus (IPS) in prior fMRI studies. However, a direct test of its causal involvement in temporal orienting is still lacking. The present study tackled this issue by transiently perturbing left IPS activity with either online (Experiment 1) or offline (Experiment 2) transcranial magnetic stimulation (TMS). In both experiments, participants performed a temporal orienting task, alternating between blocks in which a temporal cue predicted when a subsequent target would appear and blocks in which a neutral cue provided no information about target timing. In Experiment 1 we used an online TMS protocol, aiming to interfere specifically with cue-related temporal processes, whereas in Experiment 2 we employed an offline protocol whereby participants performed the temporal orienting task before and after receiving TMS. The right IPS and/or the vertex were stimulated as active control regions. While results replicated the canonical pattern of temporal orienting effects on reaction time, with faster responses for temporal than neutral trials, these effects were not modulated by TMS over the left IPS (as compared to the right IPS and/or vertex regions) regardless of the online or offline protocol used. Overall, these findings challenge the causal role of the left IPS in temporal orienting of attention inviting further research on its underlying neural substrates 2023-06-05T11:00:33Z 2023-06-05T11:00:33Z 2023-04-07 journal article M. Capizzi et al. A transcranial magnetic stimulation study on the role of the left intraparietal sulcus in temporal orienting of attention. Neuropsychologia 184 (2023) 108561[https://doi.org/10.1016/j.neuropsychologia.2023.108561] https://hdl.handle.net/10481/82239 10.1016/j.neuropsychologia.2023.108561 eng http://creativecommons.org/licenses/by-nc-nd/4.0/ open access Attribution-NonCommercial-NoDerivatives 4.0 Internacional Elsevier