Post-COVID Patients With New-Onset Chronic Pain 2 Years After Infection: Cross-Sectional Study Calvache Mateo, Andrés Navas-Otero, Alba Heredia-Ciuró, Alejandro Martín-Núñez, Javier Torres Sánchez, Irene López López, Laura Valenza, Marie Carmen Background: Although pain is common in non-hospitalized post-COVID-19 syndrome, only a few studies have provided information on the pain experience of these patients. Aim: To identify the clinical and psychosocial profile associated with pain in non-hospitalized patients with post-COVID-19 syndrome. Method: In this study there were three groups: healthy control group, successfully recovered group, and post-COVID syndrome group. Pain-related clinical profile and pain-related psychosocial variables were collected. Pain-related clinical profile included: pain intensity and interference (Brief Pain Inventory), central sensitization (Central Sensitization Scale), insomnia severity (Insomnia Severity Index), and pain treatment. Pain-related psychosocial variables were: fear of movement and (re)injury (Tampa Scale for Kinesiophobia), catastrophizing (Pain Catastrophizing Scale), depression, anxiety and stress (Depression, Anxiety and Stress Scale), and fear-avoidance beliefs (Fear Avoidance Beliefs Questionnaire). Results: In all, 170 participants were included in the study (healthy control group n = 58, successfully recovered group n = 57, and post-COVID syndrome group n = 55). Post-COVID syndrome group obtained significantly worse punctuation in pain-related clinical profile and psychosocial variables than the other two groups (p < .05). Conclusions: In conclusion, patients with post-COVID-19 syndrome have experienced high pain intensity and interference, central sensitization, increased insomnia severity, fear of movement, catastrophizing, fear-avoidance beliefs, depression, anxiety, and stress 2023-06-05T07:12:32Z 2023-06-05T07:12:32Z 2023-05-22 journal article Calvache-Mateo, A., Navas-Otero, A., Heredia-Ciuró, A., Matín-Núñez, J., Torres-Sánchez, I., López-López, L., & Valenza, M. C. (2023). Post-COVID Patients With New-Onset Chronic Pain 2 Years After Infection: Cross-Sectional Study. Pain Management Nursing. https://hdl.handle.net/10481/82202 10.1016/j.pmn.2023.04.010 eng open access