Dietary exposure to endocrine disruptors in gut microbiota: A systematic review Calero-Medina, Laura Jiménez Casquet, María José Heras González, Leticia Conde Pipó, Javier López Moro, Alejandro Olea Serrano, Fátima Mariscal Arcas, Miguel Dysbiosis Endocrine disruptors Gut microbiota metabolic disease Microbial metabolites Obesogens The authors thank Layla Davies-Jimenez and Richard Davies for assistance with the English version. This paper is part of Alejandro Lopez-Moro's doctoral thesis developed under the “Nutrition and Food Sciences Program” of the University of Granada. Spain. Endocrine disrupting chemicals (EDCs) can interfere with hormonal actions and have been associated with a higher incidence of metabolic disorders. They affect numerous physiological, biochemical, and endocrinal activities, including reproduction, metabolism, immunity, and behavior. The purpose of this review was to elucidate the association of EDCs in food with the gut microbiota and with metabolic disorders. EDC exposure induces changes that can lead to microbial dysbiosis. Products and by-products released by the microbial metabolism of EDCs can be taken up by the host. Changes in the composition of the microbiota and production of microbial metabolites may have a major impact on the host metabolism. 2023-05-18T11:51:19Z 2023-05-18T11:51:19Z 2023-05-09 journal article Calero-Medina, L., Jimenez-Casquet, M. J., Heras-Gonzalez, L., Conde-Pipo, J., Lopez-Moro, A., Olea-Serrano, F., & Mariscal-Arcas, M. (2023). Dietary exposure to endocrine disruptors in gut microbiota: A systematic review. The Science of the total environment, 886, 163991. Advance online publication. https://doi.org/10.1016/j.scitotenv.2023.163991 https://hdl.handle.net/10481/81661 10.1016/j.scitotenv.2023.163991 eng http://creativecommons.org/licenses/by-nc-nd/4.0/ open access Attribution-NonCommercial-NoDerivatives 4.0 Internacional