<rdf:RDF xmlns:rdf="http://www.openarchives.org/OAI/2.0/rdf/" xmlns:ow="http://www.ontoweb.org/ontology/1#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:ds="http://dspace.org/ds/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:doc="http://www.lyncode.com/xoai" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/rdf/ http://www.openarchives.org/OAI/2.0/rdf.xsd">
   <ow:Publication rdf:about="oai:digibug.ugr.es:10481/81644">
      <dc:title>Bioconversion of Cheese Whey and Food By-Products by Phaeodactylum tricornutum into Fucoxanthin and n-3 Lc-PUFA through a Biorefinery Approach</dc:title>
      <dc:creator>Luca Russo, Giovanni</dc:creator>
      <dc:creator>Verardo, Vito</dc:creator>
      <dc:creator>Martín García, Beatriz</dc:creator>
      <dc:subject>PUFA</dc:subject>
      <dc:subject>Sustainability</dc:subject>
      <dc:subject>Food by-products</dc:subject>
      <dc:subject>Bioconversion</dc:subject>
      <dc:subject>Biorefinery</dc:subject>
      <dc:subject>Dairy wastewater</dc:subject>
      <dc:subject>Microalgae</dc:subject>
      <dc:description>This study investigates the potential of utilizing three food wastes: cheese whey (CW), beet molasses (BM), and corn steep liquor (CSL) as alternative nutrient sources for the cultivation of the diatom Phaeodactylum tricornutum, a promising source of polyunsaturated eicosapentaenoic acid (EPA) and the carotenoid fucoxanthin. The CW media tested did not significantly impact the growth rate of P. tricornutum; however, CW hydrolysate significantly enhances cell growth. BM in cultivation medium enhances biomass production and fucoxanthin yield. The optimization of the new food waste medium was conducted through the application of a response surface methodology (RSM) using hydrolyzed CW, BM, and CSL as factors. The results showed a significant positive impact of these factors (p &lt; 0.005), with an optimized biomass yield of 2.35 g L-1 and a fucoxanthin yield of 3.64 mg L-1 using a medium composed of 33 mL L-1 of CW, 2.3 g L-1 of BM, and 2.24 g L-1 of CSL. The experimental results reported in this study showed that some food by-products from a biorefinery perspective could be utilized for the efficient production of fucoxanthin and other high-added-value products such as eicosapentaenoic acid (EPA).</dc:description>
      <dc:date>2023-05-18T09:40:27Z</dc:date>
      <dc:date>2023-05-18T09:40:27Z</dc:date>
      <dc:date>2023-03-19</dc:date>
      <dc:type>journal article</dc:type>
      <dc:identifier>Russo, G.L.; Langellotti, A.L.; Verardo, V.; Martín-García, B.; Oliviero, M.; Baselice, M.; Di Pierro, P.; Sorrentino, A.; Viscardi, S.; Marileo, L.; et al. Bioconversion of Cheese Whey and Food By-Products by Phaeodactylum tricornutum into Fucoxanthin and n-3 Lc-PUFA through a Biorefinery Approach. Mar. Drugs 2023, 21, 190. [https://doi.org/ 10.3390/md21030190]</dc:identifier>
      <dc:identifier>https://hdl.handle.net/10481/81644</dc:identifier>
      <dc:identifier>10.3390/md21030190</dc:identifier>
      <dc:language>eng</dc:language>
      <dc:rights>http://creativecommons.org/licenses/by/4.0/</dc:rights>
      <dc:rights>open access</dc:rights>
      <dc:rights>Atribución 4.0 Internacional</dc:rights>
      <dc:publisher>MDPI</dc:publisher>
   </ow:Publication>
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