Impacts of metal stress on extracellular microbial products, and potential for selective metal recovery Zadeh, Parvin Hasani Serrano Moral, Antonio Extracellular polymeric substances Soluble microbial products Metal binding properties Metal stress response Selective metal recovery Harnessing microbial capabilities for metal recovery from secondary waste sources is an eco-friendly and sus- tainable approach for the management of metal-containing wastes. Soluble microbial products (SMP) and extracellular polymeric substances (EPS) are the two main groups of extracellular compounds produced by microorganisms in response to metal stress that are of great importance for remediation and recovery of metals. These include various high-, and low, molecular weight components, which serve various functional and structural roles. These compounds often contain functional groups with metal binding potential that can attenuate metal stress by sequestering metal ions, making them less bioavailable. Microorganisms can regulate the content and composition of EPS and SMP in response to metal stress in order to increase the compounds specificity and capacity for metal binding. Thus, EPS and SMP represent ideal candidates for developing tech- nologies for selective metal recovery from complex wastes. To discover highly metal-sorptive compounds with specific metal binding affinity for metal recovery applications, it is necessary to investigate the metal binding affinity of these compounds, especially under metal stressed conditions. In this review we critically reviewed microbial EPS and SMP production as a response to metal stress with a particular emphasis on the metal binding properties of these compounds and their role in altering metal bioavailability. Furthermore, for the first time, we compiled the available data on potential application of these compounds for selective metal recovery from waste streams 2023-05-18T06:31:55Z 2023-05-18T06:31:55Z 2023-02-07 journal article P. Hasani Zadeh et al. Impacts of metal stress on extracellular microbial products, and potential for selective metal recovery. Ecotoxicology and Environmental Safety 252 (2023) 114604. [https://doi.org/10.1016/j.ecoenv.2023.114604] https://hdl.handle.net/10481/81624 10.1016/j.ecoenv.2023.114604 eng info:eu-repo/grantAgreement/EC/H2020/Marie Sklodowska-Curie 861088 http://creativecommons.org/licenses/by/4.0/ open access Atribución 4.0 Internacional Elsevier