Effect of an intervention New Medicine Service to improve adherence in the Spanish community pharmacies: a protocol of a pragmatic randomised trial González Vera, María de los Angeles Valcárcel Cabrera, María del Carmen Narbona, Javier López Sánchez-Cantalejo Garrido, María del Carmen Vaquero Prada, Juan Pedro Olry de Labry Lima, Antonio Community Pharmacy Services Professional Role Medication Adherence Servicios de Farmacia Comunitaria adherencia intervención protocolo All authors have made substantial contributions to all of the following: (1) the conception and design of the study, acquisition of data, analysis and interpretation of data, (2) drafting the article and revising it critically, and (3) final approval of the version to be submitted. The authors declare that the manuscript has not been submitted in whole or in part to other journals at the same time as Ars Pharmaceutica. ClinicalTrials.gov Identifier: NCT04195191 Introduction: Non-adherence to medications is one of the challenges health systems faces. Patients with poor adherence to treatment fail to benefit from effective medication, and this is associated with reductions in quality of life, poorer outcomes, increased hospitalisations, deaths, and, consequently, higher healthcare costs. Community pharmacies are shown to be key elements in improving adherence to prescribed medications, optimising patient outcomes and increasing the efficiency of care. Objectives: (1) assess the effectiveness of the New Medicine Service (NMS) intervention delivered by community pharmacists to improve adherence to treatment in patients who have been prescribed a new medicine for a specific chronic condition; and (2) to conduct an economic evaluation of this intervention. Methods: A pragmatic randomized clinical trial at community pharmacy-level (clusters) will be performed. Patients identified in the collaborating community pharmacy as starting treatment for the following conditions, will be invited to join the study: chronic obstructive pulmonary disease, hypertension, diabetes mellitus or on an anticoagulant/antiplatelet agent. The intervention is based on the pharmacist-patient communication, aiming to assess the patient’s relationship with his/her new prescription, and identify potential issues, concerns and false beliefs or expectations. Ethics and dissemination: The study protocol has been reviewed and ethics approval obtained from the regional ethics committee. The results from this study will be actively disseminated through manuscript publications and conference presentations. Introducción: La falta de adherencia a los medicamentos es uno de los desafíos a los que se enfrentan los sistemas de salud. Los pacientes con mala adherencia al tratamiento no se benefician de la eficacia de la medicación, lo que se asocia con peor calidad de vida, aumento en hospitalizaciones y muertes y, en consecuencia, mayores costes sanitarios. Se ha demostrado que las farmacias comunitarias son elementos clave para mejorar la adherencia a los medicamentos prescritos, optimizar los resultados en pacientes con enfermedades crónicas y aumentar la eficiencia de la atención sanitaria. Objetivos: (1) evaluar la efectividad de la intervención Asistencia a Nuevos Medicamentos (ANM) administrada por farmacéuticos comunitarios para mejorar la adherencia al tratamiento en pacientes a los que se les ha recetado un nuevo medicamento para una enfermedad crónica específica; y (2) realizar una evaluación económica de esta intervención. Métodos: Se realizará un ensayo clínico pragmático aleatorizado a nivel de farmacia comunitaria (clúster). Se invitará a unirse al estudio a los pacientes identificados en la farmacia comunitaria que inicien tratamiento para: enfermedad pulmonar obstructiva crónica, hipertensión arterial, diabetes mellitus o en tratamiento con un anticoagulante/ antiagregante plaquetario. La intervención se basa en la comunicación farmacéutico-paciente, con el objetivo de evaluar la relación del paciente con su nuevo medicamento, e identificar posibles problemas, preocupaciones y falsas creencias-expectativas. Ética y difusión: Se ha obtenido el dictamen favorable del Comité de Ética de la Investigación Biomédica de Andalucía. Los resultados de este estudio se difundirán activamente a través de publicaciones y presentaciones en congresos. 2023-05-10T09:51:41Z 2023-05-10T09:51:41Z 2022-04-22 info:eu-repo/semantics/article González Vera, M de los A.; et al. Effect of an intervention New Medicine Service to improve adherence in the Spanish community pharmacies: a protocol of a pragmatic randomised trial. Ars Pharm, 63(3): 263-273 (2022). [10.30827/ars.v63i3.24625] 2340-9894 https://hdl.handle.net/10481/81443 10.30827/ars.v63i3.24625 eng http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess Attribution-NonCommercial-NoDerivatives 4.0 Internacional Universidad de Granada, Facultad de Farmacia.