Presence of Parabens in Different Children Biological Matrices and Its Relationship with Body Mass Index Moscoso Ruiz, Inmaculada Gálvez Ontiveros, Yolanda Samaniego Sánchez, Cristina Monteagudo Sánchez, Celia Zafra Gómez, Alberto Rivas Velasco, Ana María Parabens Obesogens Children Urine Nail Saliva The following supporting information can be downloaded at: https: //www.mdpi.com/article/10.3390/nu15051154/s1, Table S1: Comparison between control and cases included/not included subjects This work was carried out within the framework of Proyecto cofinanciado FEDER-ISCIII PI20/01278, Proyecto cofinanciado FEDER-Consejería de Salud y Familias, Junta de Andalucía PE-0250-2019, Proyecto cofinanciado FEDER-Consejería de Transformación Económica, Industria, Conocimiento y Universidades, Junta de Andalucía P18-RT-4247 and INTRAIBS-2021-02 funded by ibs.GRANADA. Parabens have been accepted almost worldwide as preservatives by the cosmetic, food, and pharmaceutical industries. Since epidemiological evidence of the obesogenic activity of parabens is weak, the aim of this study was to investigate the association between parabens exposure and child- hood obesity. Four parabens (methylparaben/MetPB, ethylparaben/EthPB, propylparaben/PropPB, and butylparaben/ButPB) were measured in 160 children’s bodies between 6 and 12 years of age. Parabens measurements were performed with ultrahigh-performance liquid chromatography cou- pled with tandem mass spectrometry (UHPLC-MS/MS). Logistic regression was used to evaluate risk factors for elevated body weight associated with paraben exposure. No significant relation was detected between children’s body weight and the presence of parabens in the samples. This study confirmed the omnipresence of parabens in children’s bodies. Our results could be a basis for future research about the effect of parabens on childhood body weight using nails as a biomarker due to the ease of its collection and its non-invasive character. 2023-05-10T08:52:44Z 2023-05-10T08:52:44Z 2023-02-24 journal article Moscoso-Ruiz, I.; Gálvez-Ontiveros, Y.; Samaniego-Sánchez, C.; Almazán Fernández de Bobadilla, V.; Monteagudo, C.; Zafra-Gómez, A.; Rivas, A. Presence of Parabens in Different Children Biological Matrices and Its Relationship with Body Mass Index. Nutrients 2023, 15, 1154. [https://doi.org/10.3390/ nu15051154] https://hdl.handle.net/10481/81438 10.3390/nu15051154 eng http://creativecommons.org/licenses/by/4.0/ open access Atribución 4.0 Internacional MDPI