Comparative Study on the Oxidative Stability of Encapsulated Fish Oil by Monoaxial or Coaxial Electrospraying and Spray-Drying Rahmani Manglano, Nor Elena Guadix Escobar, Emilia María García Moreno, Pedro Jesús Encapsulation Omega-3 polyunsaturated fatty acids Lipid oxidation Delivery systems Spray-drying Monoaxial electrospraying Coaxial electrospraying The impact of the encapsulation technology on the oxidative stability of fish-oil-loaded capsules was investigated. The capsules (ca. 13 wt% oil load) were produced via monoaxial or coaxial electrospraying and spray-drying using low molecular weight carbohydrates as encapsulating agents (e.g., glucose syrup or maltodextrin). The use of spray-drying technology resulted in larger capsules with higher encapsulation efficiency (EE > 84%), whilst the use of electrospraying produced encapsulates in the sub-micron scale with poorer retention properties (EE < 72%). The coaxially electrosprayed capsules had the lowest EE values (EE = 53–59%), resulting in the lowest oxidative stability, although the lipid oxidation was significantly reduced by increasing the content of pullulan in the shell solution. The emulsion-based encapsulates (spray-dried and monoaxially electrosprayed capsules) presented high oxidative stability during storage, as confirmed by the low concentration of selected volatiles (e.g., (E,E)-2,4-heptadienal). Nonetheless, the monoaxially electrosprayed capsules were the most oxidized after production due to the emulsification process and the longer processing time. 2023-03-24T10:03:50Z 2023-03-24T10:03:50Z 2023-01-24 journal article Rahmani-Manglano, N.E... [et al.]. Comparative Study on the Oxidative Stability of Encapsulated Fish Oil by Monoaxial or Coaxial Electrospraying and Spray-Drying. Antioxidants 2023, 12, 266. [https://doi.org/10.3390/antiox12020266] https://hdl.handle.net/10481/80802 10.3390/antiox12020266 eng http://creativecommons.org/licenses/by/4.0/ open access Atribución 4.0 Internacional MDPI