Poor Cognitive Agility Conservation in Obese Aging People Pardo Moreno, Teresa Mohamed Mohamed, Himan García Lara, Rubén A. Suleiman Martos, Sami Ramos Rodríguez, Juan José Obesity Metabolic syndrome Cognitive function Dementia Mental agility Life expectancy has been boosted in recent decades at expenses of increasing the ageassociated diseases. Dementia, for its incidence, stands out among the pathologies associated with aging. The exacerbated cognitive deterioration disables people from carrying out their daily lives autonomously and this incidence increases exponentially after 65 years of age. The etiology of dementia is a miscellaneous combination of risk factors that restrain the quality of life of our elderly. In this sense, it has been established that some metabolic pathologies such as obesity and diabetes act as a risk factor for dementia development. In contrast, a high educational level, as well as moderate physical activity, have been shown to be protective factors against cognitive impairment and the development of dementia. In the present study, we have evaluated the metabolic composition of a population between 60–90 years old, mentally healthy and with high academic degrees. After assessing agility in mental state, we have established relationships between their cognitive abilities and their body composition. Our data support that excess body fat is associated with poorer maintenance of cognition, while higher percentages of muscle mass are associated with the best results in the cognitive tests. 2023-02-20T08:18:24Z 2023-02-20T08:18:24Z 2023-01-05 journal article Pardo-Moreno, T... [et al.]. Poor Cognitive Agility Conservation in Obese Aging People. Biomedicines 2023, 11, 138. [https://doi.org/10.3390/biomedicines11010138] https://hdl.handle.net/10481/80063 10.3390/biomedicines11010138 eng http://creativecommons.org/licenses/by/4.0/ open access Atribución 4.0 Internacional MDPI