The Impact of Sleep Quality on Mood Status and Quality of Life in Patients with Alopecia Areata: A Comparative Study Sánchez Díaz, Manuel Díaz Calvillo, Pablo Soto Moreno, Alberto Molina Leyva, Alejandro Arias Santiago, Salvador Antonio Alopecia Areata Sleep quality Quality of life Mood status disturbances Alopecia Areata (AA) is a chronic condition which has been associated with poor quality of life and mood status disturbances. The aim of this study is to compare the sleep quality between AA patients and controls, and to analyze the impact of poor sleep quality on patients with AA regarding mood status disturbances, quality of life and sexuality. A cross-sectional study including patients suffering from mild-to-severe AA and sex- and age-matched healthy controls was performed. Socio-demographic and clinical variables, sleep quality, quality of life, sexual disfunction, anxiety, depression and personality were collected using validated questionnaires. A total of 120 participants (60 patients and 60 controls) were included. Patients with AA showed worse sleep scores than controls (p = 0.003), as well as higher rates of anxiety and depression (p < 0.05). After a multivariate analysis, a worse sleep quality was found to be linked to anxiety, depression, a poorer quality of life and a type D personality score independently of the disease severity. In light of the results, patients with AA have a worse sleep quality than healthy controls. A poor sleep quality is associated with anxiety, depression and a worse quality of life, therefore being a general marker of a poor quality of life. Screening for sleep disturbances in specialized units could be useful to detect patients who could benefit from additional psychological support. 2022-11-29T07:54:45Z 2022-11-29T07:54:45Z 2022-10-12 journal article Sánchez-Díaz, M... [et al.]. The Impact of Sleep Quality on Mood Status and Quality of Life in Patients with Alopecia Areata: A Comparative Study. Int. J. Environ. Res. Public Health 2022, 19, 13126. [https://doi.org/10.3390/ijerph192013126] https://hdl.handle.net/10481/78163 10.3390/ijerph192013126 eng http://creativecommons.org/licenses/by/4.0/ open access Atribución 4.0 Internacional MDPI