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      <dc:title>A multicomponent reaction platform towards multimodal near-infrared BODIPY dyes for STED and fluorescence lifetime imaging</dc:title>
      <dc:creator>Fernández, Antonio</dc:creator>
      <dc:creator>González García, María del Carmen</dc:creator>
      <dc:creator>Espinar Barranco, Laura</dc:creator>
      <dc:creator>González Vera, Juan Antonio</dc:creator>
      <dc:creator>Orte Gutiérrez, Ángel</dc:creator>
      <dc:description>We report a platform combining multicomponent reaction synthesis and automated cell-based&#xd;
screening to develop biocompatible NIR-BODIPY fluorophores. From a library of over 60 fluorophores,&#xd;
we optimised compound NIRBD-62c as a multimodal probe with suitable properties for STED superresolution&#xd;
and fluorescence lifetime imaging. Furthermore, we employed NIRBD-62c for imaging&#xd;
trafficking inside cells and to examine how pharmacological inhibitors can alter the vesicular traffic&#xd;
between intracellular compartments and the plasma membrane.</dc:description>
      <dc:date>2022-09-26T10:31:28Z</dc:date>
      <dc:date>2022-09-26T10:31:28Z</dc:date>
      <dc:date>2022-08-25</dc:date>
      <dc:type>journal article</dc:type>
      <dc:identifier>RSC Chem. Biol., 2022, Advance Article. DOI: [10.1039/d2cb00168c]</dc:identifier>
      <dc:identifier>https://hdl.handle.net/10481/76963</dc:identifier>
      <dc:identifier>10.1039/d2cb00168c</dc:identifier>
      <dc:language>eng</dc:language>
      <dc:rights>http://creativecommons.org/licenses/by/4.0/</dc:rights>
      <dc:rights>open access</dc:rights>
      <dc:rights>Atribución 4.0 Internacional</dc:rights>
      <dc:publisher>Royal Society of Chemistry</dc:publisher>
   </ow:Publication>
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