Impact of the COVID-19 Pandemic on the Diagnosis and Prognosis of Melanoma Martínez López, Antonio Díaz Calvillo, Pablo Cuenca Barrales, Carlos Montero Vílchez, Trinidad Sánchez Díaz, Manuel Buendía Eisman, Agustín Arias Santiago, Salvador Antonio Melanoma COVID-19 SARS-CoV-2 Pandemic Background: Early detection of melanoma is one of the main diagnostic goals of dermatologists worldwide, due to the increasing incidence of the disease in our environment. However, the irruption of the SARS-CoV-2 pandemic has posed a challenge to global healthcare, forcing systems to focus their resources on the fight against COVID-19. Methods: Retrospective cohort study. The exposed cohort were patients diagnosed with melanoma in the year after the general confinement in Spain (15 March 2020) and the unexposed cohort were patients with melanoma diagnosed in the previous year. Results: 130 patients were included. No differences were observed between demographic characteristics in both cohorts. The mean Breslow of melanoma before the onset of the pandemic was 1.08, increasing to 2.65 in the year after the onset of the pandemic (p < 0.001). On the other hand, the percentage of melanomas in situ decreased from 38.96% to 16.98% in the year after the declaration of the state of alarm in Spain. Conclusions: The SARS-CoV-2 outbreak has led to a reduction in the early diagnosis of melanoma, with an increase in invasive melanomas with poor prognosis histological factors. This could lead to an increase in melanoma-related mortality in the coming years in our environment. 2022-09-12T09:20:12Z 2022-09-12T09:20:12Z 2022-07-19 info:eu-repo/semantics/article Martinez-Lopez, A... [et al.]. Impact of the COVID-19 Pandemic on the Diagnosis and Prognosis of Melanoma. J. Clin. Med. 2022, 11, 4181. [https://doi.org/10.3390/jcm11144181] http://hdl.handle.net/10481/76639 10.3390/jcm11144181 eng http://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess Atribución 4.0 Internacional MDPI