Circadian Variation of Blood Pressure in Patients with Chronic Musculoskeletal Pain: A Cross-Sectional Study Navarro Ledesma, Santiago García Ríos, María Del Carmen Pruimboom, Leo Pain Chronic pain Chronobiologic indicators Circadian rhythm disorders Blood pressure Musculoskeletal disorders The aim of this study was to analyze the impact of circadian variation of blood pressure (BP) in patients with chronic musculoskeletal pain (CPM). A further purpose was to study differences in circadian variation of BP between genders and the correlation between BP circadian variation and pain. We performed a cross-sectional, observational study in which seventy-five participants with CMP participated. Circadian variation in BP was calculated using the diurnal/nocturnal BP ratio, and all participants used validated self-measurement BP devices. The Numeric Pain Rating Scale was used to assess pain perception. All circadian BP values from participants who suffered from CPM followed pathologic cardiovascular parameters (BP ratio < 10%). When comparing BP ratios between genders, statistically significant differences were found (p = 0.011). BP itself did not correlate with pain in any subgroup. Circadian variations of BP in those suffering from CMP are shown and new possibilities of research and treatment are proposed. 2022-06-30T09:46:25Z 2022-06-30T09:46:25Z 2022-05-26 journal article Navarro-Ledesma, S... [et al.]. Circadian Variation of Blood Pressure in Patients with Chronic Musculoskeletal Pain: A Cross-Sectional Study. Int. J. Environ. Res. Public Health 2022, 19, 6481. [https://doi.org/10.3390/ijerph19116481] http://hdl.handle.net/10481/75739 10.3390/ijerph19116481 eng http://creativecommons.org/licenses/by/4.0/ open access Atribución 4.0 Internacional MDPI