Treating Gingival Recessions Using Coronally Advanced Flap or Tunnel Techniques with Autografts or Polymeric Substitutes: A Systematic Review and Meta-Analysis Toledano Osorio, Manuel Muñoz Soto, Esther Toledano Pérez, Manuel Vallecillo Rivas, Marta Vallecillo, Cristina Ramos García, Pablo Osorio Ruiz, Raquel Connective tissue Coronal advanced flap Gingival recession Guided periodontal tissue regeneration Surgical flaps Systematic review Tunnel technique This work was supported bythe Ministry of Economy and Competitiveness and European Regional Development Fund [Project PID2020-114694RB-100 MINECO/AEI/FEDER/UE]. M. Toledano-Osorio holds a FPU fellowship from the Ministry of Universities (FPU20/00450). Gingival recessions are a prevalent oral mucosa alteration. To solve this pathology, palatal mucosa or polymeric soft tissue substitutes are used when performing coronal advanced flap (CAF) or tunnel (TUN) surgical techniques. To evaluate which is the most successful approach, a literature review and meta-analysis were conducted. For the electronic search the National Library of Medicine, the Cochrane Oral Health Group Trials Register, EMBASE and WOS were used. Pooled data for the percentage of root coverage was collected and weighted means were calculated. Heterogeneity was determined using the Higgins (I2) statistic and a random-effects model was applied. Thirteen studies were included in the systematic review (12 randomized and 1 controlled clinical trials) in which both techniques (394 patients) were compared with a follow-up of 4 to 12 months. Galbraith and Baujat plots were used to control for the presence of potential outliers. After performing the meta-analysis (11 studies), the mean root coverage was similar when using the TUN or CAF techniques (p = 0.49). The only differences between the two were found for single recessions, where CAF offered a higher percentage of root coverage (mean difference = 4.98%; p = 0.006). There were no differences when applying an autograft or a polymeric substitute with either of the two tested surgical techniques (p = 0.445). 2022-05-04T10:57:42Z 2022-05-04T10:57:42Z 2022-04-02 info:eu-repo/semantics/article Toledano-Osorio, M... [et al.]. Treating Gingival Recessions Using Coronally Advanced Flap or Tunnel Techniques with Autografts or Polymeric Substitutes: A Systematic Review and Meta-Analysis. Polymers 2022, 14, 1453. [https://doi.org/10.3390/polym14071453] http://hdl.handle.net/10481/74691 10.3390/polym14071453 eng http://creativecommons.org/licenses/by/3.0/es/ info:eu-repo/semantics/openAccess Atribución 3.0 España MDPI