Layer-by-Layer Integration of Zirconium Metal-Organic Frameworks onto Activated Carbon Spheres and Fabrics with Model Nerve Agent Detoxification Properties Gil San Millán, Rodrigo Delgado López, Pedro José López Maya, Elena Martín Romera, Javier David Barea Martínez, Elisa María Rodríguez Navarro, Jorge Andrés Composite Thin film Chemical warfare agent Filter Protective garments Heterogeneous catalysis This research was funded by the Directorate for Planning, Technology, and Innovation (SDG PLATIN) from the Directorate General of Armaments and Material (DGAM) of the Spanish Ministry of Defense, COINCIDENTE Program exp. 1003219007500—NBQD2. The authors also acknowledge EU Feder funding, MINECO (CTQ2017-84692-R and PID2020-113608RB-I00), Universidad de Granada (Plan Propio de Investigación), and Junta de Andalucia (P18-RT-612). Funding for open access charge: Universidad de Granada/CBUA. We report the controlled synthesis of thin films of prototypical zirconium metal-organic frameworks [Zr6O4(OH)4(benzene-1,4-dicarboxylate-2-X)6] (X = H, UiO-66 and X = NH2, UiO-66-NH2) over the external surface of shaped carbonized substrates (spheres and textile fabrics) using a layer-by-layer method. The resulting composite materials contain metal-organic framework (MOF) crystals homogeneously distributed over the external surface of the porous shaped bodies, which are able to capture an organophosphate nerve agent simulant (diisopropylfluorophosphate, DIFP) in competition with moisture (very fast) and hydrolyze the P-F bond (slow). This behavior confers the composite material self-cleaning properties, which are useful for blocking secondary emission problems of classical protective equipment based on activated carbon. 2021-11-29T08:12:17Z 2021-11-29T08:12:17Z 2021-10-13 journal article ACS Appl. Mater. Interfaces 2021, 13, 50491−50496. [https://doi.org/10.1021/acsami.1c12095] http://hdl.handle.net/10481/71800 10.1021/acsami.1c12095 eng http://creativecommons.org/licenses/by/3.0/es/ open access Atribución 3.0 España American Chemical Society