Autonomic Imbalance in Lymphoma Survivors Vargas Román, Keyla Cortés Martín, Jonathan Sánchez García, Juan Carlos Rodríguez Blanque, Raquel De la Fuente-Solana, Emilia I. Díaz Rodríguez, Consuelo Lourdes Lymphoma cancer HRV Autonomic nervous system Non-Hodgkin lymphoma Among the types of blood cancers, non-Hodgkin lymphoma is the most common. The usual treatments for this type of cancer can cause heart failure. A descriptive observational study was conducted that included 16 non-Hodgkin lymphoma survivors and 16 healthy controls matched by age and sex. Vagal tone was evaluated in the short term with a three-channel Holter device, and the time and frequency domains were analyzed following a previously accepted methodology to evaluate cardiac autonomic balance. The results of the analysis revealed that the standard deviation of the NN interval (F = 6.25, p = 0.021) and the square root of the mean of the sum of the differences between NN intervals (F = 9.74, p = 0.004) were significantly higher in healthy subjects than in lymphoma survivors. In the heart rate variability (HRV) index, there were no significant differences between the groups (F = 0.03, p = 0.85), nor in the parameters of the frequency domains LF (F = 1.94, p = 0.17), HF (F = 0.35, p = 0.55), and the ratio LF/HF (F = 3.07, p = 0.09). HRV values were lower in non-Hodgkin lymphoma survivors in the first year after treatment, resulting in autonomic imbalance compared to healthy paired subjects. 2021-10-18T07:12:58Z 2021-10-18T07:12:58Z 2021 journal article Vargas-Román, K.; Cortés-Martín, J.; Sánchez-García, J.C.; Rodríguez-Blanque, R.; De La Fuente-Solana, E.I.; Díaz-Rodríguez, L. Autonomic Imbalance in Lymphoma Survivors. J. Clin. Med. 2021, 10, 4391. https://doi.org/ 10.3390/jcm10194391 http://hdl.handle.net/10481/70911 10.3390/jcm10194391 eng http://creativecommons.org/licenses/by/3.0/es/ open access Atribución 3.0 España MDPI